Initial clinical experience with helical tomotherapy for head and neck cancer.
نویسندگان
چکیده
BACKGROUND To report a single-institutional experience with the use of helical tomotherapy (HT)-based intensity-modulated radiotherapy (IMRT) for head and neck cancer. METHODS Seventy-seven consecutive patients were treated with HT for squamous cell carcinoma of the head and neck to a median dose of 66 Gy (range, 60 to 72 Gy). Megavoltage CT scans were obtained as part of an image-guided registration protocol for patient alignment before each treatment. Concurrent chemotherapy was administered to 48 patients (62%). RESULTS The 2-year estimates of overall survival, local-regional control, and disease-free survival were 82%, 77%, and 71%, respectively. Spatial evaluation of local-regional failures revealed that 16 of the 18 patients who progressed in the primary site or neck failed in the high-dose planning target volume (PTV). CONCLUSIONS HT appears to achieve clinical outcomes comparable to contemporary series reporting on IMRT for head and neck cancer.
منابع مشابه
Comparison of survival rates between patients treated with conventional radiotherapy and helical tomotherapy for head and neck cancer
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عنوان ژورنال:
- Head & neck
دوره 31 12 شماره
صفحات -
تاریخ انتشار 2009